基于正交试验的桔梗多糖口服液的研制

摘要

Platycodon grandiflorum has rich pharmacological and healthy functions. The extraction of platycodon polysaccharides was carried out by ultrasound assisted method, optimization formula was obtained by orthogonal test as follows: platycodon polysaccharides 0.6%, sugar 3%, honey 3%, citric acid 0.1%;composite stabilizer formula is as follows: guar gum 0.06%, CMC-Na 0.06%, xanthan gum 0.07%, potassium sorbate 0.02%.Prepared platycodon polysaccharide oral liquid is light yellow clear liquid, tastes sweet and sour, its quality indicators are in line with the corresponding standards.%桔梗具有丰富的药理和保健功能。采用超声辅助法提取桔梗多糖，通过正交试验得到最优化配方为桔梗多糖0.6%、白砂糖3%、蜂蜜3%、柠檬酸0.1%，复合稳定剂配方为：瓜尔豆胶0.06%、CMC-Na 0.06%、黄原胶为0.07%，添加0.02%的山梨酸钾，得到的桔梗多糖口服液为淡黄色澄清液体，味道酸甜适口，口感圆润，各项质量指标均符合相应的标准。