Objective To analyze the effect of endoscopy in treatment of acute upper gastrointestinal hemorrhage, and to explore the risk factors of recurrent hemorrhage after treatment, in order to provide the scientific basis for reducing the risk of rebleeding and mortality. Methods 150 cases of acute upper gastrointestinal hemorrhage patients whose first endoscopic treatment for hemostasis were successful were selected and divided into two groups according to recurrent hemorrhage conditions: recurrent hemorrhage group (39 cases) and non-hemorrhage group (111 cases). The clinical data of two groups were compared, the risk factors of recurrent hemorrhage were analyzed by univariate and multivariate analysis. Results The results of multivariate analysis showed that the risk factors of upper gastrointestinal rebleeding included malignant tumor hemorrhage, endoscopic active hemorrhage, lesion sprayed bleeding, the large hemorrhage volume, low hemoglobin count, and inadequate supportive treatment. Conclusions There has many risk factors of recurrent hemorrhage of acute upper gastrointestinal hemorrhage after treatment. For patients with risk factors, risk assessment should be attached attention and prevention and treatment should be timely taken.%目的：分析内镜治疗急性上消化道出血的效果，探讨治疗后再出血的危险因素，为减少再出血风险和病死率提供依据。方法选取首次内镜治疗止血成功的150例急性上消化道出血患者作为研究对象，根据再出血情况分为再出血组（39例）和未再出血组（111例），比较两组患者的临床资料，通过单因素和多因素分析影响再出血的危险因素。结果多因素分析结果显示，影响上消化道再出血的危险因素包括恶性肿瘤出血、内镜下活动性出血、病灶喷射样出血、出血量大、血红蛋白计数低、支持治疗不足。结论急性上消化道内镜治疗后再出血的危险因素有许多，对于存在危险因素的患者应重视风险评估，及时防护处理。
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