165例发作性睡病患者的临床特征分析

摘要

目的 研究分析山东省立医院睡眠医学中心确诊的165例发作性睡病患者的临床特征,提高临床医师对发作性睡病的认识.方法 选取2015年1月至2018年8月我院睡眠医学中心诊治的165例发作性睡病患者的临床资料,进行回顾性分析.结果 165例发作性睡病患者中男性为女性的2.3倍,伴猝倒的患者占84.24％,高于既往研究;患者大部分来自于山东省,以八月、二月、三月就诊者最多;发病年龄、五联征发生概率及其他临床表现与既往研究基本相同.结论 发作性睡病是一种相对罕见的神经系统疾病,发病早,临床表现多种多样,病因不明.应尽早诊断、治疗,并加强对患者的管理教育,以提高其生活质量.%Objective The clinical features of 165 patients with narcolepsy diagnosed in the sleep medicine center of Shandong Provincial Hospital to improve clinical physicians'' understanding of narcolepsy.Methods To study the clinical data of 165 patients with narcolepsy who were diagnosed and treated in the sleep medicine center of our hospital from January 2015 to August 2018 were analyzed retrospectively.Results In 165 cases of narcolepsy, the number of man was 2.3times higher than that of woman and patients with cataplexy accounted for 84.24％, which were more than that of previous studies.Most of the patients were from Shandong province, and most were diagnosed in August, February and March.Age of onset, incidence rate of the syndrome pentad of narcolepsy and other clinical manifestations were basically the same as those of the previous studies.Conclusion Narcolepsy is a relatively rare nervous system disease, whose onset is accompanied with diverse clinical manifestations and unknown etiology.Early diagnosis, treatment and management of patients should be strengthened to improve their quality of life.