人工合成微生物混菌体系的研究进展

摘要

合成生物学正在从设计构建基本功能元件和模块，逐步向着从头设计人工细胞及构建人工生物群落的方向发展，人工合成微生物混菌体系已经成为未来合成生物学研究的重要方向。本文综述了人工构建微生物群落生态关系、群落时空动态和分布式计算等基础研究的进展。同时，微生物混菌体系在医药、环境、能源等领域发挥着不可替代的作用，人工合成混菌体系在相关领域也表现出巨大的应用潜力。%Synthetic biology is developing from designing and building functional parts and modules to re-designing an artificial cell and constructing synthetic microbial consortia. Synthetic microbial consortium represents the tendency of synthetic biology. This review summarizes recent advances in engineering microbial consortia, including basic ecological relationships, spatio-temporal dynamics and distributed computations. In addition, microbial consortia play an indispensible role in the areas of medicine, environment and energy. Synthetic microbial consortia also have great potential in these relevant areas.