Objective To explore the clinical effect and safety of different concentrations of ropivacaine in interscalene brachial plexus block. Methods 105 patients scheduled for hand or forehand surgery from January 2009 to December 2011 were randomly divided into three groups including the group A(n = 35) , B(n = 35) and C(n = 35). Interscalene brachial plexus block guided by B type ultrasound was performed separately with 0. 25 % ,0. 375% and 0. 50% ropivacaine 30 mL in three groups. The anesthetic and block effect and side effect were analyzed and compared among 3 groups. Results Compared with the group A,the time of sensory and motor block was remarkably decreased,and the duration time of analgesia was significantly increased in the group B and C(P< 0. 05). The VAS scores at 12 h after block in the group B and C were significantly lower than those in the group A(P<0. 05). The rate of adverse reactions was 8. 6% in the group A and 11. 4% in the group B,which was significantly lower than 34. 3% in the group C(P<0. 05). Conclusion The concentration of 0. 375% ropivacaine in interscalene brachial plexus block can achieve good anesthetic and block effect,and reduce the adverse reactions.%目的 探讨不同浓度罗哌卡因应用于肌间沟臂丛神经阻滞的有效性及安全性.方法 选择2009年1月至2011年12月在该院接受手部或前臂手术的患者105例,随机分为A、B、C 3组,每组各35例.均采用B超引导下肌间沟臂丛神经阻滞,分别给予0.25%、0.375%、0.50%罗哌卡因30 mL.比较3组患者的麻醉效果.结果 与A组比较,B组、C组感觉和运动阻滞时间明显缩短,镇痛持续时间明显延长(P<0.05);阻滞后12 h B组、C组视觉模拟标尺法(VAS)评分显著低于A组(P<0.05).A组和B组不良反应的发生率分别为8.6%和11.4%,显著低于C组的34.3%(P<0.05).结论 采用0.375%罗哌卡因应用于肌间沟臂丛神经阻滞,能达到良好的麻醉和阻滞效果,且可减少不良反应的发生.
展开▼
