脐带多能干细胞与女性卵巢功能维护

摘要

卵巢作为女性的性腺，在女性体内负责生殖和内分泌的功能，卵巢功能障碍会严重影响女性生理和身心健康。干细胞能可分化成多种组织细胞，其在早衰卵巢的微环境下能“因地制宜”的分化为卵巢细胞，发挥卵巢细胞正常功能，维持卵巢的正常形态，防止卵巢萎缩变形。此外，干细胞再生的卵巢细胞可以对脑垂体分泌的促性腺激素做出及时、正确的反应，维护内激素水平处于平衡状态。%As female gonad , ovary is responsible for the reproduction and endocrine .Ovarian dysfunction will affect woman ’ s physical and mental health seriously .Stem cells can differentiate into various tissue cells and ovarian germ cells in premature ovarian failure ( POF) microenvironment , which play normal function and maintain morphology of ovary to prevent deformation and atrophy .In addition , when mesenchymal stem cells ( MSCs ) are differentiated into ovarian germ cells successfully , they can make responses to the secretion of pituitary gonadotropins timely and accurately in order to keep hormone levels in balance .