氨基甲酸酯型猪去氧胆酸分子钳的微波合成及其对卤素阴离子的识别

摘要

Five novel carbamate-type molecular tweezers (4a ~ 4e) based on hyodeoxycholic acid were synthesized using hyodeoxycholic acid as spacer to bridge different aromatic amines under microwave irradiation. The structures were characterized by ' H NMR, IR, MS and elemental analysis. The recognition properties of 4 on halogen anions were investigated by UV-Vis titration method. The results showed that 4 not only formed 1 :1 complex with halogen anions, but also exhibited good selectivity for halogen anions with selective sequence of I- > Br- > Cl-.%在微波辐射条件下,以猪去氧胆酸为隔离基,芳香胺为手臂,通过三光气桥连,合成了五个新型猪去氧胆酸分子钳(4a～4e),其结构经1H NMR,IR,MS和元素分析表征.紫外光谱滴定法的研究结果表明,4对卤素阴离子均具有良好的识别能力,选择顺序依次为I-＞ Br-＞ Cl-;主客体之间形成1∶1型超分子配合物,识别作用的主要推动力为氢键.