远端胃癌术后胃瘫多因素分析

摘要

Objective To analyze and investigate the potential factors of postoperative gastroparesis syn⁃drome(PGS). Methods One thousand and 46 patients having undergone radical distal gastrectomy were re⁃viewed, and twelve factors involved in PGS through multi-factors logistic regression analysis and single factor Chi-square test were used in the analysis. Results PGS was occurred in 56 cases (5.45%). Sexual, periopera⁃tive hyperglycemia, preoperative malnutrition, anxiety, preoperative pyloric obstruction, Billroth II gastrointesti⁃nal anastomosis, postoperative hypoproteinemia and vagus nerve stem reserved, the 8 factors, were related to PGS, meanwhile the factor of vagus nerve stem reserved was thought to be a protective element factor preventing PGS. Apparently the elderly was much more inclined to have PGS. Conclusion PGS is induced by many fac⁃tors after operation for gastric cancer.It is important to deal with these factors in preventing or reducing the oc⁃currence of PGS.%　　目的：探讨分析引起远端胃癌术后胃瘫综合征的可能因素。方法：回顾分析行远端胃癌根治术的1046例患者的临床资料，通过多因素Logistic回归分析和单因素χ2检验分析12个可能引起胃瘫发生的危险因素。结果：性别、围手术期高血糖、术前营养不良、焦虑、术前幽门梗阻、毕II式吻合、术后第2天低蛋白血症与胃瘫发生有关；术中迷走神经干保留是术后胃瘫的保护性因素。结论：远端胃癌根治术后胃瘫由多种因素共同作用，积极处理这些因素有助于预防和减少术后胃瘫的发生。