Obesity, related cardiometabolic disorders (including high blood pressure, dyslipidemia and high fasting glucose etc.) and unhealthy lifestyles are now epidemic. These cardiovascular risk factors can track from childhood into adulthood, thereby increasing risk of cardiovascular disease in adulthood. Thus, it is important and necessary to establish children cohort study, to examine the effects of childhood cardiovascular risk factors on abnormal subclinical cardiovascular structure and function in adolescence and adulthood, then to take specific and effective measures for prevention, intervention and control. This will have important public health implications for the prevention of adult cardiovascular disease.%肥胖、相关代谢性疾病(包括高血压、高血脂、高血糖等)以及不健康的生活方式在儿童中呈现流行趋势.这些心血管病危险因素从儿童期到成年期存在"轨迹"现象,增加成年期心血管疾病风险.因此,有必要建立儿童随访队列,探讨儿童期的各种心血管病危险因素对青少年期和成年期的亚临床心血管结构和功能异常的影响,并进行有针对性的预防、干预和控制.这对于成人心血管疾病的防控具有重要公共卫生学意义.
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Department of Epidemiology, School of Public Health, Shandong University/Children Cardiovascular Research Center of Shandong University, Ji′nan 250012, China;