住院新生儿弓形虫与巨细胞病毒感染发生率调查

摘要

目的探讨住院新生儿弓形虫（TOX）与巨细胞病毒(CMV)感染发生率与危害性。方法用酶联免疫吸符试验(ELISA)方法检测新生儿血清CMV-IgG/IgM抗体与TOX-IgG/IgM抗体。结果住院新生儿CMV-IgG阳性率86.7%,CMV-IgM阳性率5.2%，TOX-IgG阳性率13.9%,TOX-IgM阳性率0.4%。CMV/TOX-IgG(IgM)阳性患儿临床以早产儿、小于胎龄儿、新生儿肺炎、败血症、脑病、肝炎综合征等为主要表现，且患儿母亲妊娠期间有不同程度发热、异常饮食史、宠物接触史。结论住院新生儿TOX与CMV感染发生率较高，新生儿TOX和CMV感染可引起多种临床表现。%Objective To study the morbidity of Toxoplasma (TOX) andCytomegalovirus (CMV) infection in in-patient infants and their clinical character. Methods The serum CMV-IgG/IgM and TOX-IgG/IgM ware measured by enzyme linked immunosorbant assay (ELISA) Results The positive rate of CMV-IgG, CMV-IgM, TOX-IgG and TOX-IgM were 86.7%, 5.2%,13.9% and 0.4% respectively in in-patient infants. The main clinical manifestication of neonatal TOX and CMV infection were premature, small for gestational age, neonatal pneumonia, sepsis, encephalopathy, hepatitis syndrome. Conclusion TOX and CMV infection were widely noticed in in-patient infants, and their potential damage should be greatly considered in our clinical practice.