氟桂利嗪联合手法复位治疗后半规管原发性良性阵发性位置性眩晕的临床疗效观察

摘要

Objective To evaluate the effectiveness of flunarizine combined with Epley maneuver in treating posterior semicircular canal benign paroxysmal positional vertigo (PC-BPPV). Methods Ninety six patients diagnosed with PC-BPPV were randomly selected to receive either the Epley canalith repositioning maneuvers alone or in combination with flunarizine treatment. Results All patients experienced complete resolution or significant improvement of vertigo symptoms after a single repositioning treatment session, with an overall success rate of 71.88%. The overall success rate reached to 86.45% after 4 weeks 79.16% for Epley maneuver only and 93.75% for Epley maneuver combined with flunarizine.. Symptoms recurred in 8 patients during the 3 months follow-up period 18.42% for patients receiving Epley maneuver treatment alone and 2.22% for those receiving Epley maneuver combined with flunarizine. Conclusion Combining Epley maneuver with flunarize appears to improve treatment outcomes in PC-BPPV%目的 探讨氟桂利嗪联合手法复位治疗后半规管原发性良性阵发性位置性眩晕(posterior semicircularcanal benign paroxysman positional vertigo,PC-BPPV)的治疗效果.方法 对96例原发性PC-BPPV患者随机分为单纯手法治疗(Epley管石复位法)与联合氟桂利嗪进行治疗,观察治疗效果.结果 经1次手法复位治疗后症状消失或明显减轻,一次治愈率两组基本相同.治疗4wk后,治疗组的治愈率为高于对照组(P＜0.05).随访3个月,共计有8例患者复发,总复发率为9.6％,其中治疗组为2.2％,对照组为18.4％.结论 Epley手法复位联合氟桂利嗪治疗PC-BPPV疗效显著,复发率低.