宫瘀净胶囊成型工艺研究

摘要

目的：优选除杂工艺；确定胶囊型号和装量，提供封装车间的相对湿度数据。方法：比较研究不同除杂工艺浸膏的物理性质，测定药粉的堆密度和临界相对湿度。结果：高速离心法处理后的浸膏易干燥，其药粉流动性较好，吸湿率较低。结论：选择高速离心法作为本品的除杂方法，确定选用0号空心胶囊，装量规格0.45g，封装车间的相对湿度应控制在54%以下。%OBJECTIVE：To choose the best process to clear impurity.To fix the type and filling capacity of capsule.To provide the relative humidity of workshop.METHODS:The nature of extract prepared with different methods were studied.The pile-density and critical relative humidity were determined.RESULTS:The extract that was prepared by high-speed centrifuge was easier to dry.The fluidity of the powder was better.The hygroscopicity of the powder was lower.CONCLUSION:The high-speed centrifugal method was chosen.The type of capsule was defined as 0#.The package was 0.45 gram for each capsule.The relative humidity of workshop was below 54%.