目的 评价经直肠超声(TRUS)联合实时弹性成像(TRTE)与MR联合MRS检查对不同Gleason评分前列腺癌( Pca)的诊断价值.方法 对73例Pca患者、49例良性前列腺增生患者(BPH组)进行TRUS联合TRTE、MR联合MRS检查,根据Gleason分级,将Pca患者分为低危组(n=21)、中危组(n=24)、高危组(n=28),以手术或穿刺活检病理组织学为标准,对检查结果进行统计分析.结果 Pca高危组的结节彩色血流最大峰值流速及阻力指数明显高于BPH组(P＜0.05);中危组及高危组Pca的弹性应变率比值明显高于BPH组(P＜0.05).TRUS联合TRTE的诊断符合率稍低于MRI联合MRS,但差异无统计学意义(P＞0.05).结论 TRTE及MRS有助于Pca的诊断和鉴别诊断,但须密切结合TRUS及MR.%Objective To observe the diagnostic value of transrectal ultrasonography (TRUS) with transrectal real-time elastography (TRTE) and MR with MRS on prostate cancer (Pea) with different Gleason scores. Methods Totally 122 patients underwent TRUS with TRTE and MR with MRS. Seventy-three patients with Pea were divided into low risk group (n=21) , moderate risk group (n=24) and high risk group (n = 28) according to Gleason sores. The rest 49 patients were found with benign prostatic hyperplasia (PHB group). The results of each method were compared with pathological diagnosis from surgery or biopsy. Results Peak systolic velocity and resistance index of Pea in high risk group were higher than that in PHB group (F＜0. 05). The strain ratio of elastography of moderate risk group and high risk group were higher than that in PHB group (P＜0. 05). The diagnostic accordance rate of TRUS with TRTE was lower than that of MR with MRSt but there was no significant difference (P>0. 05). Conclusion TRTE and MRS can help to diagnosis and differential diagnosis of Pea, but need to combine with TRUS and MR.
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