Combination therapeutic product, pharmaceutical composition, use of a combination therapeutic product, and method for the treatment or prophylaxis of prostate cancer

摘要

"COMBINATION THERAPEUTIC PRODUCT, PHARMACEUTICAL COMPOSITION, USE OF A COMBINATION THERAPEUTIC PRODUCT, AND METHOD FOR PROSTATE TREATMENT OR PROPHYLAXY". The invention relates to a combination therapeutic product comprising a non-steroidal antiandrogen and an epidermal growth factor receptor (EGFR) tyrosine kinase (TKI) inhibitor for simultaneous, sequential or separate use in the synergistic treatment or prophylaxis of cancer. prostate. In particular, the product of the invention is effective in inhibiting the transformation of prostate cancer cells from a hormone dependent state to a hormone independent state. The product of the invention is further expected to have a beneficial effect in preventing the onset of prostate cancer in men genetically predisposed to the disease.