目的 评价内镜难治性胃肠道出血介入诊疗的安全性和有效性.方法 对31例内镜难治性胃肠道出血患者行DSA检查,明确出血部位后行出血动脉栓塞治疗,并评价其安全性和疗效.结果 血管造影发现出血阳性率为80.65％(25/31),28例行栓塞止血治疗,1次栓塞止血成功率75.00％(21/28),2次栓塞总成功率82.14％(23/28).7例介入术后行外科手术,包括2例空肠间质瘤及5例胃恶性肿瘤.4例胃恶性肿瘤患者介入术后30日内再发间断出血,其中2例因基础疾病致心肺衰竭死亡.除1例胃肠吻合术后吻合口出血患者栓塞止血术后出现吻合口瘘,经支持治疗后恢复出院,余患者未出现严重胃肠缺血坏死.结论 介入诊疗对胃肠道出血的诊断及止血治疗高效、安全,尤其对胃恶性肿瘤出血亦能取得良好效果,可作为内镜难治性胃肠道出血的一种较好的诊治手段.%Objective To evaluate the diagnostic and therapeutic value and safety of transcatheter arterial angiography and embolization in patients with endoscopic refractory gastrointestinal bleeding.Methods Thirty-one cases of endoscopic refractory gastrointestinal bleeding were performed DSA and treated with transcatheter arterial angiography and embolization.The safty and efficacy was evaluated.Results Angiographic positive rate of bleeding was 80.65％ (25/31);28 cases was treated with embolization.The success rate of first embolization was 75.00％ (21/28),and the total success rate was 82.14 ％ (23/28) by the second embolization.Seven patients received surgical resection after interventional therapy,including 2 cases of jejunal stromal tumors and 5 cases of gastric malignant tumors.Four cases of gastric cancer patients underwent rebleeding within 30 days after interventional therapy,of which 2 died of heart or lung function failure due to basic diseases.Except for 1 patient of anastomotic bleeding after gastrointestinal anastomosis occurred anastomotic fistula after embolization,who recovery with the support treatment,no other cases occurred serious gastrointestinal ischemic necrosis.Conclusion Interventional diagnosis and treatment for gastrointestinal bleeding hemostasis is effective and safety,and also can achieve good results especially for malignant gastric tumor hemorrhage,which can be used for endoscopic refractory gastrointestinal bleeding patients.
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