Glypican-3与原发性肝癌的关系研究进展

摘要

近年来有关Glypican-3(GPC3)与原发性肝癌(HCC)关系的研究逐年增多,发现GPC3无论在原发性肝癌病人的血清中还是肿瘤组织中均有较高的表达,对原发性肝癌的诊断具有较高的灵敏性和特异性.其表达水平与原发性肝癌的预后也有一定的关系.同时,GPC3也为原发性肝癌的治疗带来了新的思路.%In recent years, the study about the relationship between Glypican-3 (GPC3) and hepatocellular carcinoma (HCC) increased year by year. GPC3 has higher expression in the blood serum and tumor tissues of patients with HCC, and it has higher sensitivity and specificity in the diagnosis of HCC. The expression of GPC-3 also has a certain relationship with the prognosis of HCC. Meanwhile, GPC3 provided a novel for the treatment of HCC.