肠道微生态重建在炎症性肠病治疗中的意义

摘要

Although the etiology and pathogenesis of inflammatory bowel disease ( IBD) have not been fully elucida-ted, while the important role of abundant microbiota in the intestinal inflammation is a broad consensus .However, most previous studies have focused on the intestinal bacteria induced intestinal inflammation , while ignored the role of other microorganisms (fungi, viruses and parasites, etc) in IBD.Moreover, the dietary factors in improving the intestinal mi-croecological environment and symptoms of IBD have been ignored .In recent years , the “fecal microbiota transplanta-tion”, as a whole method of improving the intestinal microecological environment in treatment of IBD has a good effect . Thus, in this paper , the significance of rebuilding intestinal microecology in the treatment of IBD was reviewed .%尽管炎症性肠病（ inflammatory bowel disease ， IBD）的病因和发病机制尚未完全明确，但肠道中定植的大量微生物在肠道疾病发生中有着重要作用已是共识。既往的研究大多只关注细菌导致肠道炎症，而忽略了肠道中真菌、病毒、寄生虫等其他微生物对IBD的影响；并且饮食因素在改善肠道微生态环境和IBD症状上的重要作用也被很多研究者所忽略。近年来，“粪菌移植”作为一种整体的改善患者肠道微生态环境的方法也在IBD治疗过程中有良好的疗效。因此，本文就肠道微生态重建在IBD治疗中的意义作一概述。