2型糖尿病合并肺结核患者外周血T淋巴细胞亚群分析及临床护理对策

摘要

目的 探讨2型糖尿病合并肺结核患者外周血T淋巴细胞亚群的特点,为临床护理提供证据支持.方法 利用流式细胞术对41例2型糖尿病合并肺结核患者(DM+ LTB组)及60例单纯肺结核患者(LTB组)的外周血淋巴细胞亚群进行检测,并以健康成年人为对照组,对检测结果进行统计学分析.结果 DM+ LTB组和LTB组的外周血淋巴细胞亚群绝对值均显著低于正常对照组(P＜0.05),DM+ LTB组CD3+CD4+/CD3+CD8+比值显著高于LTB组(P＜0.05).结论 2型糖尿病合并肺结核患者存在比较严重的细胞免疫功能紊乱.护理人员应从加强健康教育、心理及饮食等方面加强护理,提高患者的机体免疫力.%Objective To investigate the character of peripheral blood T lymphocyte subset of tuberculosis patients with type 2 diabetes mellitusas providing evidence to support clinical care.Methods Use flow cytometry to analysis peripheral blood lymphocyte subsets of 41 patients with type 2 diabetes mellitus patients with pulmonary tuberculosis (DM + LTB group),and 60 cases of simple pulmonary tuberculosis (LTB group),and in healthy adults as a control group.The test results were analyzed statistically.Results Absolute lymphocyte subsets value of DM + LTB group and LTB group were significantly lower than the control group (P ＜ 0.05),CD3 + CD4 +/CD3 + CD8 + ratio of DM + LTB group was significantly higher than the LTB group (P ＜ 0.05).Conclusion Tuberculosis patients with type 2 diabetes show more severe T lymphocyte immune dysfunction.Nurses should improve the patient's immunity from strengthening health education,strengthen psychological care and diet care.