金昌队列人群癌症疾病负担分析

摘要

目的 掌握金昌队列人群常见癌症的疾病负担,为制定该队列癌症防治措施、减轻癌症疾病负担提供基础数据.方法 收集金昌队列人群2001-2013年癌症全死因资料及2001-2010年癌症住院患者资料,应用死亡率、潜在减寿年(PYLL)、潜在工作损失年(WPYLL)、直接经济负担分析癌症造成的疾病负担.结果 该队列人群13年癌症平均死亡率顺位前5位为肺癌(78.06/10万)、胃癌(38.03/10万)、肝癌(37.23/10万)、食管癌(19.60/10万)、结直肠癌(9.53/10万);前5位恶性肿瘤PYLL(人年)、WPYLL(人年)依次为肺癌(3 480.33、1 161.00)、肝癌(2 809.03、l 475.00)、胃癌(2 120.54、844.00)、食管癌(949.61、315.00)、结直肠癌(539.90、246.00).该队列10年恶性肿瘤人均例次住院费用依次为胃癌(8 102.23元)、食管癌(7 135.79元)、结直肠癌(7 064.38元)、乳腺癌(6 723.53元)、肺癌(6 309.39元).结论 金昌队列人群疾病负担较重的前五位癌症为肺癌、胃癌、肝癌、食管癌、结直肠癌,其中尤以肺癌的疾病负担最重.%Objective To understand the disease burden caused by cancers in Jinchang cohort,and develop effective strategies for cancer prevention and control in this population.Methods The cancer mortality data from 2001 to 2013 and the medical records for cancer patients from 2001 to 2010 in Jinchang cohort were collected.The disease burden caused by cancer was analyzed by using mortality rate,potential years of life lost (PYLL),working PYLL (WPYLL),and direct economic burden.Results During 2001-2013,in Jinchang cohort,the five leading cancers ranked by mortality rate were lung cancer (78.06/100 000),gastric cancer (38.03/100 000),liver cancer (37.23/100 000),esophageal cancer (19.06/100 000),and colorectal cancer (9.53/100 000).The five leading cancers in terms of PYLL (person-years) and WPYLL (person-years) were lung cancer (3 480.33,1 161.00),liver cancer (2 809.03,1 475.00),gastric cancer (2 120.54,844.00),esophageal cancer (949.61,315.00),and colorectal cancer (539.90,246.00).From 2001 to 2010,the five leading cancers in term of average daily cost of hospitalization were gastric cancer (8 102.23 Yuan),esophageal cancer (7 135.79 Yuan),colorectal cancer (7 064.38 Yuan),breast cancer (6 723.53 Yuan),and lung cancer (6 309.39 Yuan).Conclusions The cancers common causing higher disease burden in Jinchang cohort were lung cancer,gastric cancer,liver cancer,esophageal cancer and colorectal cancer.The lung cancer disease burden was the highest.