Objective To investigate the effect of Zuogui pill combined with clomiphene citrate on ovarian function after treatment of polycystic ovary syndrome (PCOS). Methods 86 patients with PCOS were randomly divided two groups. The study group were treated with Zuogui pill combined with clomiphene, and the control group were treated with clomiphene. The changes of ovarian endometrium, ovulation rate and pregnancy rate were compared in the two groups. Results After treatment, the endometrial thickness and Gonen type A endometrium in the study group were significantly better than that in the control group, the cervical mucus score in the study group was higher than that in the control group; the ovulation rate in the observation group was higher than that in the control group (P<0.05); the number of mature follicles and pregnancy rate had no significant difference in the two groups. Conclusion Zuogui pill combined with clomiphene citrate in the treatment of PCOS can effectively promote follicular growth, improve the quality of follicles, increase the thickness of endometrium, improve the morphology, increase the ovulation rate, the pregnancy rate also has a positive effect.%目的 探讨左归丸联合克罗米芬治疗多囊卵巢综合征(PCOS)后对患者排卵功能产生的影响.方法 将86例PCOS患者均分为2组,研究组使用左归丸联合克罗米芬治疗,对照组单纯使用克罗米芬进行治疗.观察2组诱排卵日子宫内膜的变化情况、排卵率和妊娠率.结果 研究组治疗后子宫内膜厚度和Gonen A型子宫内膜比例均明显优于对照组,宫颈粘液评分高于对照组;观察组排卵率高于对照组(P<0.05);2组患者成熟卵泡个数和妊娠率比较差异无统计学意义.结论 左归丸联合克罗米芬治疗PCOS,可有效改善患者排卵环境,提高排卵率,对妊娠率也有积极的作用.
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