氨溴索治疗慢性阻塞性肺疾病及干预措施分析

摘要

Objective To observe the effect of ambroxol hydrochloride combined with intervention in chronic obstructive pulmonary disease and evaluate its clinical effect. Methods A total of 88 patients with chronic obstructive pulmonary disease (COPD) who were treated in Changxing Hospital of Zhejiang Province from March 2014 to April 2017 were randomly divided into study group and control group. The control group was treated with ambroxol, and the study group was given comprehensive nursing intervention on the basis of control group. The clinical treatment of the two groups was observed.Results After treatment, the total effective rate of the treatment group was 95.45％ (42/44), the control group was 77.27％(34/44), the difference was statistically significant (P<0.05); there were no significant differences in blood gas analysis (PaO2, PEF) and lung function (MVV, Fres, Zrs, R5-R20, Cdyn) before treatment, after treatment, the improvement of the indicators in the study group was significantly better than the reference group (P<0.05). Conclusion Ambroxol combined with comprehensive nursing intervention for chronic obstructive pulmonary disease, can effectively improve the clinical treatment effect, help to improve lung function, promote the recovery of the disease, with clinical application value.%目的 观察氨溴索联用干预在慢性阻塞性肺疾病中的应用,评价其临床效果.方法 选取浙江省医疗健康集团长兴医院2014年3月～2017年4月收治的88例慢性阻塞性肺疾病患者,采用数字表随机法分为研究组与参照组,各44例.参照组给予氨溴索治疗,研究组在参照组基础上给予综合性护理干预,观察2组患者临床治疗情况.结果 经治疗后,研究组治疗总有效率为95.45％(42/44),参照组为77.27％(34/44),差异具有统计学意义(P<0.05);2组治疗前血气分析(PaO2、PEF)及肺功能指标(MVV、Fres、Zrs、R5-R20、Cdyn)等指标差异无统计学意义,治疗后研究组各指标改善情况明显优于参照组(P<0.05).结论 氨溴索联用综合性护理干预应用于慢性阻塞性肺疾病中,可有效提高临床治疗效果,有助于改善患者肺功能,促进疾病恢复,具有临床应用与推广价值.