目的：分析彩超引导下聚桂醇泡沫硬化剂治疗静脉畸形的临床疗效。方法：选择笔者医院2012年11月～2013年6月收治的静脉畸形患者96例，其中婴幼儿35例，成人及儿童61例，分别行彩超引导下畸形管腔内注射聚桂醇泡沫硬化剂，观察治疗后畸形管腔闭合情况及吸收情况。96例患者均在彩超引导下分次、多部位成功注射聚桂醇泡沫硬化剂，每日1次，每次2～6ml ，总疗程4～8次，疗程结束3个月后复查。结果：97.9%的患者经此方法治疗后，畸形血管腔全部或者部分闭塞吸收，肿块萎缩，颜色消退。治疗后2例患者出现轻微静脉炎症，经抗炎治疗后好转。2例患者因畸形静脉表浅，出现局部表皮小面积坏死，经对症处理后愈合。结论：聚桂醇泡沫硬化剂治疗静脉畸形临床疗效满意，合理应用该药物可显著提高静脉畸形的治疗效果。%Objective To analyze clinical efficacy of lauromacrogol foam sclerotherapy under ultrasound - guided for venous malformation. Methods 96 patients with venous malformations attended this study in our hospital from November 2012 to June 2013. 35 cases are infants,and 61 cases are adults or children.All the patients were performed lauromacrogol foam injection into the deformity venous lumen under ultrasound guidance and then observed closure and absorption conditions of the venous lumens, respectively. The regimen divided to 4- 8 times and multi- sites, and 2- 6ml every time, Q.D. After the end of treatment,the vascular malformations absorption conditions were re- checked again 3 months later. Results 97.9% of patients displayed that abnormal vessel lumen part or total absorption,atrophy or discoloration.2 patients showed mild vein inflammation which relieved after anti- inflammatory treatment. Other 2 patients suffered localized epidermal necrosis cause of superficial venous malformation,but it healed quickly after symptomatic treatment. Conclusion Lauromacrogol foam sclerotherapy to venous malformations could obtain satisfactory clinical efficacy. Rational application of this medication could significantly improve the efficacy of venous malformation.
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