目的：调查分析北京地区青少年心室预激及预激综合征患病率。 方法：对北京市西城区和海淀区19484名15~20岁青少年（北京市西城区中学高一年级和职业中学新生、北京大学新入学的本科生）进行心电图筛查、诊断及分型，并对心电图异常者进行随访。 结果：一共获得19389份合格心电图，其中心室预激及预激综合征患者30例（0.15%），男性患者17例（0.17%），女性患者13例（0.13%），男、女性患病率之间的差异无统计学意义（χ2=0.495，P>0.05）；6例（0.03%）伴有阵发性心悸，记录到室上性心动过速的预激综合征2例（0.01%）。30例心室预激及预激综合征患者中，A型心室预激16例（53.33%）， B型心室预激14例（46.67%），男、女性患病类型无明显差异（χ2=4.693，P>0.05）。平均随访2.5年（1.5~3年）期间，未发生恶性心律失常事件。 结论：本研究中北京地区15~20岁青少年心室预激和预激综合征患病率为0.15%，患病率和患病类型无明显性别差异。%Objective:To study the prevalence of pre-excitation and Wolff-Parkinson-White (WPW) syndrome in adolescents in Beijing area. Methods: A total of 19 484 adolescents at the age of (15-20) years from Xicheng district of Beijing and the freshmen from Peking University were enrolled for our survey; 12-lead electrocardiography (ECG) screening was conducted and the diagnosis, classification of pre-excitation, WPW syndrome were recorded. The follow-up study was performed in relevant patients. Results: There were 19 389 qualiifed ECG obtained, among them, 30 (0.15%) patients with ventricular pre-excitation and WPW syndrome identiifed including 17 male (0.17%) and 13 (0.13%) female, the prevalence between male and female was similar (χ2=0.495,P>0.05). There were 6/19389 (0.03%) patients with palpitation and 2 (0.01%) documented by super-ventricular tachycardia. There were 16/30 (53.33%) patients with type A and 14(46.7%) with type B ventricular pre-excitation, the prevalence between male and female was similar (χ2=4.693,P>0.05). The patients were followed-up at the mean of 2.5 (1.5-3) years and no malignant arrhythmia events occurred. Conclusion: In this cohort survey, prevalence of pre-excitation and WPW syndrome is about 0.15% in adolescents from (15-20) years in Beijing area; the prevalence is similar between male and female subjects.
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