四种医院制剂微生物限度检查法验证试验

摘要

目的：建立四种医院制剂的微生物限度检查方法。方法按照《中国药典》2010年版一部附录微生物限度检查法进行试验，对四种医院制剂进行了微生物限度检查方法的验证。结果通过试验建立了四种医院制剂的微生物限度检查方法。结论复方大承气口服液、防风解毒口服液可采用常规法，呋柳擦剂、复方土荆皮酊可采用薄膜过滤法检查微生物限度。%Objective To establish microbial limit test of 4 hospital preparations.Methods 4 hospital preparations was received microbial limit test according to microbial limit test in appendix I of 2010 edition of Chinese Pharmacopoeia.Results Microbial limit test of 4 hospital preparations was established by experiment.Conclusion Compound Dachengqi Oral and Detoxification Oral can adopt routine methods to test microbial limit.Fu Liu liniment and Compound tincture pseudolaric can adopt membrane filtration method to test microbial limit.