早期肠内营养在提高重型颅脑损伤患者营养状况中的效果及对并发症的影响

摘要

Objective To evaluate the effect of early nutrition on the floor to improve the nutritional status of patients with severe craniocerebral injury and the influence on complications.Methods 88 cases of severe craniocerebral injury patients in our hospital,were randomly divided into observation group and control group,sugar and GCS score between the two groups,and record the occurrence of complications.Results The group after treatment,serum total protein,serum albumin,hemoglobin,random blood glucose,intracranial pressure and GCS score before treatment compared with the same group differences were statistically significant (P<0.05),and the control group after treatment,the difference had statistical significance (P<0.05);observation group diarrhea and electrolyte disorders,pulmonary infection and stress ulcer incidence rate is lower than the control group,there are differences statistically significant (P<0.05).ConclusionEnteral nutritional support can effectively improve the clinical symptom of patients in early and severe craniocerebral injury patients,reduce the incidence of complications.%目的：评价早期场内营养在提高重型颅脑损伤患者营养状况中的效果及对并发症的影响。方法选取2011年5月～2014年4月我院收治的重型颅脑损伤患者共计88例，随机分为观察组和对照组，其中观察组44例，采用肠内营养支持治疗，对照组44例，给予肠外营养支持治疗，观察并比较两组患者治疗前后血清总蛋白、血清白蛋白、血红蛋白、平均颅内压、随机血糖及GCS评分差异，并记录两组患者并发症发生情况，所有数据录入统计学软件进行分析比较。结果两组治疗后各项指标均有改善，对照组血清总蛋白、血红蛋白、随机血糖、颅内压及GCS评分的值与同组治疗前差异具有统计学意义（P＜0.05），而血清白蛋白值治疗后与治疗前比较差异无统计学意义（P＞0.05）。观察组治疗后血清总蛋白、血清白蛋白、血红蛋白、随机血糖、颅内压及GCS评分与同组治疗前相比差异均有统计学意义（P＜0.05），与对照组治疗后差异有统计学意义（P＜0.05）；两组治疗过程中发生的并发症主要包括腹泻、电解质紊乱、肺部感染及应激性溃疡，经统计分析，观察组腹泻、电解质紊乱、肺部感染发生率与对照组相比较差异无统计学意义（P＞0.05），观察组应激性溃疡的发生率与对照组相比较差异具有统计学意义（x2=4.423，P=0.036）。结论对于重型颅脑损伤的患者早期给予肠内营养支持可有效改善患者临床症状，降低并发症的发生率，值得在临床上予以推广。