精液白细胞与不育症之间的关系研究

摘要

目的:探讨精液白细胞的检出率与不育症之间关系,以提供临床参考.方法:回顾性分析我院2008 年2 月~2011 年2 月收治的180 例男性不育症患者临床资料,选取我院同期正常生育的男性健康体检者180 例作为对照组,取其精液采用瑞-姬染色,油镜进行白细胞及其他细胞形态分类,分析精液白细胞异常患者、精液白细胞正常患者、对照组等精液动态指标并进行统计处理.结果:精液白细胞异常组患者精液液化异常、精液黏稠度、精液pH 值、精子凋亡率、解脲支原体及沙眼支原体感染阳性率均高于正常生育组和精液白细胞正常组,而精液量、精子密度、精子活率、精子活力等方面均低于正常生育组和精液白细胞正常组(P<0.05 或P<0.01).精液白细胞异常组精液运动参数明显低于精液白细胞正常组,两组比较差异有高度统计学意义(P<0.01).结论:精液白细胞影响精液质量造成不育症.%Objective: To investigate the relationship between infertility and semen white blood cells, and provide reference for clinic. Methods: Clinical data of 180 male infertility patients and 180 cases of healthy male (control group) in our hospital from February 2008 to February 2011 were analyzed retrospectively, the semen was dyed with Wright -Giemsa, white blood cells and other morphological cells were classify by oil immersion. Semen dynamic indicators were analyzed of patients with abnormal semen white blood cells, patients with normal semen white blood cells, and patients in control group. Results: Semen liquefaction, abnormal sperm viscosity, semen pH value, sperm apoptosis rate, solution urea my-coplasma and trachoma mycoplasma infection of patients with abnormal sperm white blood cells were significantly higher than those of normal birth group and normal semen white blood cells group, and sperm density, sperm quantity, live rate, sperm motility were significantly lower than those of normal birth group and normal semen white blood cells group (P<0.05 or P<0.01). Sperm movement parameters of abnormal semen white blood cells group was lower than the normal group, the differences were significant (P<0.01). Conclusion: The impact of sperm white blood cells cause infertility by affecting the quality of semen.