肺炎支原体感染与儿童哮喘的相关性研究

摘要

目的:初步探讨肺炎支原体与儿童哮喘的相关性.方法:采用金标快速检测法测定136例哮喘急性发作患儿血清肺炎支原体特异性抗体IgM(MP-IgM),并选择同期上呼吸道感染患儿138例作为对照.结果:哮喘组MP-IgM阳性率明显高于对照组(x2=40.864,P=0.000);7岁以上儿童MP-IgM阳性率最高.结论:肺炎支原体感染与儿童哮喘有密切关系,应注意哮喘急性发作期患儿感染肺炎支原体的可能,阿奇霉素对MP-IgM阳性哮喘疗效显著,可作为 有效治疗药物推广应用.%Objective: To investigate the correlativity beteween mycoplasma pneumonia infection and cough variant asthma (CVA) in chidren.Methods: 136 casea with CVA were sejected as the CVA group and 138 cases with acute upper respiratory infection as the control group.The MP-IgM antibody level was detemined by DICFA.Results: The positive rate for MP-IgM in CVA group was markedly higher than that of die control group (Xz=40.864,P=O.OOO), and above 7-years-old chidrens were highest.Conclusion: Mycoplasma pneumonia infection and cough variant asthma are closely cirrelated,Archmycin has remarkable effect for MP-IgM with positive rate, and can be to use for an effective medicine.