伴攻击行为酒精依赖患者的神经认知功能损害特征分析

摘要

Objective To study the characteristics of neurocognitive impairment in alcohol-dependent patients with aggressive behavior.Methods 100 patients with alcohol dependence were enrolled in Brain Hospital of Hu'nan Province from January 2015 to January 2016.The patients were divided into two groups according to the explicit behavior attack scale.The 50 patients with aggressive behavior were considered as the observation group,50 patients without aggressive behavior were considered as the control group.According to the Wechsler adult intelligence scale,Stroop test and Wisconsin card sorting test,the cognitive function impairment,memory function,attention and executive function of the two groups were compared.Results The mean score of Wechsler adult intelligence scale and memory quotient in the observation group were significantly lower than those of the control group,the differences were statistically significant (P ＜ 0.05).The ST-CW test score and the ST-C test score in the observation group were significantly lower than those of the control group,the differences were statistically significant (P ＜ 0.05).The working memory capacity score and the cognitive transfer ability score of the observation group were significantly lower than those of the control group,the differences were statistically significant (P ＜ 0.05).Conclusion Alcohol-dependence can impair the cognitive function of the patients.The neurocognitive dysfunction of alcohol-dependence patients with aggressive behavior is more serious.Most patients show the reduction of memory function,attention and executive function.Cognitive impairment of consciousness is also an important factor that leads to aggressive behavior in patients.%目的 分析伴攻击行为酒精依赖患者的神经认知功能损害特征.方法 选取2015年1月～2016年1月湖南省脑科医院收治的酒精依赖患者100例为研究对象,根据患者外显行为攻击量表评分分为两组,其中伴攻击行为的50例为观察组,不伴攻击行为的50例为对照组.根据韦氏成人智力量表、Stroop测验以及威斯康星卡片分类测验比较两组患者的记忆功能、注意力以及执行功能等神经认知功能损害情况.结果 观察组患者韦氏成人智力量表平均得分、记忆商数明显低于对照组患者,差异有统计学意义(P＜0.05).观察组患者Stroop测验评分中,ST-CW测验评分、ST-C测验评分明显低于对照组患者,差异有统计学意义(P＜0.05).观察组患者威斯康星卡片分类测验(WCST)评分中,工作记忆能力评分、认知转移能力评分明显低于对照组患者,差异有统计学意义(P＜0.05).结论 酒精依赖可以使患者的神志认识功能受到一定损害,而伴有攻击性行为的酒精依赖患者的神经认识功能损害更严重,多数患者表现为不同程度的记忆功能、注意力以及执行功能降低.神志认识功能的损害也是导致患者出现攻击性行为的重要相关因素.