首页> 外国专利> method for treating or preventing at least one inflammatory condition in a patient, method for inhibiting liver damage in a patient at risk of chemical liver damage from prescribed drugs or drugs of abuse, method for inhibiting nkt type i cell mediated tissue damage in a patient, method for inhibiting nkt type i cell activation, method for inhibiting nkt type i cell activation in a patient with an inflammatory disease, and method for inhibiting myeloid cell release in a patient's liver

method for treating or preventing at least one inflammatory condition in a patient, method for inhibiting liver damage in a patient at risk of chemical liver damage from prescribed drugs or drugs of abuse, method for inhibiting nkt type i cell mediated tissue damage in a patient, method for inhibiting nkt type i cell activation, method for inhibiting nkt type i cell activation in a patient with an inflammatory disease, and method for inhibiting myeloid cell release in a patient's liver

机译:在患者中治疗或预防至少一种炎症的方法,在因处方药或滥用药物而遭受化学肝损害风险的患者中抑制肝损害的方法,在患者中抑制NKT I型细胞介导的组织损伤的方法,抑制NKT I型细胞活化的方法,抑制炎性疾病患者中NKT I型细胞活化的方法以及抑制患者肝脏中髓样细胞释放的方法

摘要

The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relates to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
机译:本实施方案涉及预防和治疗炎性病症例如酒精性肝病(ALD)的方法。更具体地,本实施方案涉及通过给予视黄酸受体(RAR)激动剂来预防和治疗ALD。一些实施方案涉及他扎罗汀在预防和治疗酒精引起的肝损伤,酒精相关的肝病,脂肪肝疾病,肝脂肪变性,酒精性肝炎或酒精性肝硬化中的用途。

著录项

  • 公开/公告号BR112013033309A2

    专利类型

  • 公开/公告日2017-03-07

    原文格式PDF

  • 申请/专利权人 GLYCOREGIMMUNEINC.;

    申请/专利号BR20131133309

  • 发明设计人 VIPIN KUMAR CHATURVEDI;

    申请日2012-06-22

  • 分类号A61K31/7024;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:46

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