左心室肥大患者心电图Ptfv1值检测及其与多普勒超声心动图指标、血清指标的相关性分析

摘要

Objective To analyze left ventricular hypertrophy patients ECG P-wave terminal force in lead V1 (Ptfv1) value and its relationships with Doppler echocardiographic and serum indices. Methods Eighty-seven cases of left ventricular hypertrophy patients in the First Affiliated Hospital of Zhengzhou University between September 2011 and September 2014 were chosen as observation group, at the same time 82 cases of normal people without heart diseases were chosen as control group. Ptfv1 value, echocardiography indexes and serum marker levels were compared between the two groups and their relationships were analyzed. Results The average Ptfv1 value of the observation group was higher than that of the control group ( < 0.05). The left ventricular diameter (LAD) in the observation group was larger than that in the control group, while left ventricular end-diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were smaller than than those in the control group ( <0.05). The serum IMD and salusin-α levels in the observation group were lower than those in the control group; whereas CysC, CST and NT-proBNP levels were higher than those in the control group ( < 0.05). The absolute value of Ptfv1 had positive correlations with LAD, CysC, CST and NT-proBNP levels, but had inverse correlations with LVEDD, LVEF,IMD and Salusin-α levels ( < 0.05). Conclusions In the patients with left ventricular hypertrophy, the absolute value of ECG Ptfv1 increases, echocardiography and serum indexes are obviously abnormal, and the absolute value of Ptfv1 is in direct correlations with echocardiography and serum indexes.%目的：分析左心室肥大患者心电图V1导联P波终末电势（Ptfv1）值检测及其与多普勒超声心动图指标、血清指标的相关性。方法选取2011年9月-2014年9月于郑州大学第一附属医院心内科接受住院治疗的左心室肥大患者87例作为观察组患者。另取同期在郑州大学第三附属医院接受健康体检的、不伴有心脏疾患的正常人82例作为正常对照组。比较两组间心电图Ptfv1值、超声心动图指标、血清指标水平等差异，同时进一步分析Ptfv1值与多普勒超声心动图指标、血清指标的相关性。结果①观察组患者的平均Ptfv1绝对值高于正常对照组（<0.05）；②观察组患者的左房内径（LAD）高于正常对照组，舒张末期左室内径（LVEDD）、左室射血分数（LVEF）低于正常对照组（<0.05）；③观察组患者的血清IMD、Salusin-α水平低于正常对照组，CysC、CST、NT- proBNP水平高于正常对照组（<0.05）；④Ptfv1绝对值与LAD、CysC、CST、NT- proBNP水平呈正相关，与LVEDD、LVEF、IMD、Salusin-α水平呈负相关（<0.05）。结论左心室肥大患者心电图Ptfv1绝对值增大，超声心动图及血清指标均存在显著异常，且Ptfv1绝对值与超声心动图及血清指标值间存在直接相关性。