Left Ventricular Hypertrophy by Electrocardiography and Echocardiography in the African American Study of Kidney Disease Cohort Study.

摘要

Electrocardiogram (ECG) criteria for left ventricular hypertrophy (LVH) have low sensitivity in the general population though a high prevalence of ECG LVH has been consistently reported in African-Americans (AA). The purpose of the current study was to evaluate the test characteristics of ECG criteria among AA with hypertensive kidney disease. ECGs were read by two cardiologists at an independent core laboratory using the two Sokolow-Lyon criteria and the Cornell criteria. LVH on echocardiography was defined as a left ventricular mass index >49.2 and >46.7 g/m2.7 in men and women, respectively. Sensitivity by individual ECG criteria was 16.5% by Sokolow-Lyon-1, 19.3% by Sokolow-Lyon-2, and 24.7% by Cornell criteria with specificity ranging from 89% to 92%. Consistent with previous findings, LVH by ECG had low sensitivity in this cohort of AA with hypertensive kidney disease.