益生菌制剂治疗肝硬化高血氨症56例临床分析

摘要

ObjectiveTo investigate clinical effect of probiotics in treatment of 56 patients of cirrhosis with hyperammonemia.Methods 56 cases of liver cirrhosis with hyperammonemia in department of infectious diseases of our hospital were selected as research subjects,and were randomly divided into the control group and the experimental group.Control group was given routine treatment of liver diseases,while the experimental group was based on the control group and then given probiotics therapy.The total effective rate,blood ammonia value change and adverse events of two groups were compared.ResultsThe total effective rate of the experimental group was higher than that of control group(P < 0.05).The blood ammonia value of two groups all decreased,but the experimental group decreased significantly(P < 0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P > 0.05). Conclusion Probiotics can significantly reduce the blood ammonia in patients of cirrhosis with hyperammonemia,and the treatment method is simple and has no side effect.%目的：分析益生菌制剂对于肝硬化高血氨症疾病的治疗效果。方法本文中以56例肝硬化高血氨症患者为研究对象，病例来源于我院感染科。按随机数字评分表的分组方法将此56例患者随机平均分为两组，即对照组与实验组。对照组患者选用常规肝病治疗方法治疗，实验组患者则在对照组基础上应用益生菌制剂药物治疗。两组患者经不同方法治疗一段时间后，比较两组患者的治疗总有效率、治疗前、后的血氨值及不良反应发生情况。结果实验组肝硬化高血氨症患者经益生菌制剂治疗后，治疗总有效率高于对照组；两组患者经不同方法治疗后的血氨值均降低，但实验组治疗后下降明显，P <0.05，具有统计学意义；两组患者的不良反应发生率比较无差异，P >0.05。结论益生菌制剂可明显降低肝硬化高血氨症患者的血氨指标，且治疗方法简单、无副作用。