噻托溴铵在慢性阻塞性肺疾病急性加重期治疗的临床分析

摘要

Objective To analyze and discuss the clinical treatment effect of tiotropium Bromide in chronic obstructive lung disease at acute sever stage. then provide the theoretical basis for the future treatment of respiratory department.MethodsThe hospital took 80 patients who are with chronic obstructive lung disease at acute sever stage in this study, which were divided into divided intoobservation group and control group, 40 cases of each. During treatment,the patients of the control group take the conventional treatment, while the observation group were treated with tiotropium dry powder inhalation method on the basis of conventional treatment method for fourteen days. Then compare two groups before and after treatment in patients with pulmonary function index and dyspnea score.ResultsAfter treatment with different methods, the two groups of patients with pulmonary function and dyspnea score situation are all improved. At the same time , the patients in observation group are better than the control group. The results of comparison between the two groups was statistically signiifcant (P <0.05).ConclusionFor patients with chronic obstructive lung disease at acute sever stage, using the tiotropium Bromide can obviously improve the patient's dyspnea and improve the patients' life quality. It is with dramaticlly clinical signiifcance and should be widely applied.%目的：分析噻托溴铵在慢性阻塞性肺疾病急性加重期治疗的临床治疗效果，为今后的呼吸科治疗提供一定的理论依据。方法选取我院呼吸科收治的80例慢性阻塞性肺疾病急性加重期患者为研究对象，将其平均分为观察组和对照组，每组40例患者。在治疗过程中，对照组患者采取常规治疗措施；观察组患者在常规治疗方法的基础上采用噻托溴铵干粉剂吸入的方法，治疗14 d，比较两组患者的治疗前后肺功能指标以及呼吸困难评分情况。结果采用不同的治疗方法后，两组患者的肺功能以及呼吸困难评分情况均有改善，同时观察组的患者情况优于对照组，两组结果差异比较具有统计学意义（P＜0.05）。结论针对慢性阻塞性肺疾病急性加重期治疗的患者来说，采用噻托溴铵能够明显改善患者的呼吸困难情况，提升患者的生活质量。