温度/pH双重响应性纳米微胶囊的制备及表征

摘要

The P( NIPAM-co-AA)nanocapsules with pH/temperature sensitive were synthesized using oc-tane as template through introducing of comonomer N-isopropylacrylamide( NIPAM)and acroleic acid ( AA)into the miniemulsion polymerization of styrene( St). The structure and morphology of nanocapsules were characterized by FTIR and TEM. The influence of amount of AA on pH and temperature dual stimu-li-responsive properties of nanocapsules were studied. The results show that the P( NIPAM-co-AA)nano-capsules exhibit pH and temperature dual stimuli-responsive properties,and the lower critical solution temperature( LCST)of nanocapsules is about 40~50 ℃. The introduction of AA monomer improved the pH-sensitivity of the nanocapsules.%将N-异丙基丙烯酰胺（ NIPAM）和丙烯酸（ AA）单体引入小分子液滴正辛烷为模板的细乳液共聚体系，制备了pH/温度双重响应性P（NIPAM-co-AA）纳米微胶囊。利用红外（FTIR）、透射电镜（TEM）表征了纳米微胶囊的结构与形貌。并研究了AA含量对纳米微胶囊的温度响应性及pH敏感性的影响。结果表明，制备的纳米微胶囊具有良好的pH敏感性和温度响应性，最低临界溶解温度（ LCST）在40~50℃之间；单体AA的引入提高了纳米胶囊对pH的敏感性。