利用 microCT 研究硫化铋纳米棒在小鼠体内的分布

摘要

MicroCT 在分子影像学研究中有广泛的应用，将硫化铋纳米棒灌胃给药后，利用 microCT 对小鼠在不同时间点进行扫描，实时监测纳米材料在小鼠体内的分布和代谢。计算小鼠各组织不同时间点的 HU 值，分析获得纳米材料在小鼠不同组织内随时间变化的累积及代谢情况。%The microCT was used for scanning the mice at different times by microCT,and monitoring the real-time distribution and metabolism of nano materials in vivo after the intragastric administration of the bismuth sulfide nanorods. The CT HU values of mice tissue at different times were calculated,and the accumulation and metabolism of nano materials in mice were analyzed.