Production of Radio-gold ~(199)Au for Diagnostic and Therapeutic Applications

摘要

Production cross-sections of the ~(nat)Pt(d,x)~(199)Au reactions have been measured from a 24-MeV deuteron energy down to the threshold by using a stacked-foil activation technique combined with HPGe y-ray spectrometry. Only a partial agreement is obtained with the existing literature data. Theoretical data extracted from the TENDL-2013 library shows large discrepancy with the measured ones. Physical thick target yield for the ~(199)Au radionuclide was deduced using the measured cross-sections, and found a general agreement with the directly measured yield available in the literature. This study reveals that a low deuteron energy (<15 MeV) cyclotron and an enriched ~(198)Pt (100%) target could be used to obtain ~(199)Au in no carrier added form.