首页> 外国专利> u043fu043eu043bu0438u0433u043bu0443u0442u0430u043cu0438u043du043eu0432u044bu0435 acid, u0444u0443u043du043au0446u0438u043eu043du0430u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0435 u043au0430u0442u0438u043eu043du043du044bu043cu0438 and u0433u0438u0434u0440u043eu0444u043eu0431u043du044bu043cu0438 groups and their applications, especially therapeutic application

u043fu043eu043bu0438u0433u043bu0443u0442u0430u043cu0438u043du043eu0432u044bu0435 acid, u0444u0443u043du043au0446u0438u043eu043du0430u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0435 u043au0430u0442u0438u043eu043du043du044bu043cu0438 and u0433u0438u0434u0440u043eu0444u043eu0431u043du044bu043cu0438 groups and their applications, especially therapeutic application

机译:u043f u043e u043b u0438 u0433 u043b u0443 u0442 u0430 u043c u0304c u0430 u043b u0438 u0437 u0438 u0440 u043e u0432 u0430 u043d u043d u044b u0435 u043a u0430 u0442 u0438 u043e u043d u043d u043d u044b u043c u0438和 u0433 u0438 u0434 u0440 u043e u0444 u043e u0431 u043d u044b u043c u0438组及其应用,尤其是治疗应用

摘要

the present invention relates to new u0431u0438u043eu0434u0435u0433u0440u0430u0434u0438u0440u0443u0435u043cu044bu043c materials based on modified u043fu043eu043bu0438u0430u043cu0438u043du043eu043au0438u0441u043bu043eu0442 used, in particular, vector graphics editors act u0438u0432u043du043eu0433u043e beginning (en).the present invention is also directed to new compositions, including pharmaceutical, cosmetic, dietary foods or drugs for the protection of r u0430u0441u0442u0435u043du0438u0439,based on these u043fu043eu043bu0438u0430u043cu0438u043du043eu043au0438u0441u043bu043eu0442u0430u0445.the purpose of this invention is the provision of a new polymer materialwhich can be used as a starting product of vector graphics editors ah and which meets all the requirements: u0431u0438u043eu0441u043eu0432u043cu0435u0441u0442u0438u043cu043eu0441u0442u0438, u0431u0438u043eu0434u0435u0433u0440u0430u0434u0438u0440u0443u0435u043cu043eu0441u0442u0438,the ability to easily associate or dissolve numerous active start and release the active early in vivo.this goal is achieved by the present invention, which relates to a new u043fu043eu043bu0438u0433u043bu0443u0442u0430u043cu0430u0442u0430u043cu0438, modified u043au0430u0442u0438u043eu043du043du044bu043cu0438 groups, which, if they can be u0434u0435u043fu0440u043e u0442u043eu043du0438u0440u043eu0432u0430u043du044b are pK,equal to or more than 7, and u0433u0438u0434u0440u043eu0444u043eu0431u043du044bu043cu0438 groups containing from 8 to 30 carbon atoms.such u043fu043eu043bu0438u0433u043bu0443u0442u0430u043cu0430u0442u044b, modified u043au0430u0442u0438u043eu043du043du044bu043cu0438 groups, easy and cost-effective are particles of vector graphics editors active startedand these particles are capable of forming stable aqueous u043au043eu043bu043bu043eu0438u0434u043du044bu0435 suspension.such modified u043fu043eu043bu0438u0433u043bu0443u0442u0430u043cu0430u0442u044b have the advantage that they are less viscous than other similar polymers, while at the same time preserving ability and u0441u0441u043eu0446u0438u0438u0440u043eu0432u0430u0442u044c with squirrels, for example,with insulin. some of them u0440u0430u0441u0442u0432u043eu0440u0438u043cu044b in water in acidic ph and become insoluble at physiological ph (7.4) and should therefore be deposited in the skin in place introduction the injections.
机译:本发明涉及基于改进的 u043f u043e u043b u043b u043c的新型 u0431 u0438 u043e u0434 u0435 u0433 u0440 u0430 u0434 u0434 u0438 u0440 u0443 u0435 u0435 u043c u044b u043c u0430 u043c u0438 u043d u043e u043a u0438 u0441 u043b u043e u0442特别是矢量图形编辑器从现在开始执行 u0438 u0432 u043d u043e u0433 u043e。本发明还针对基于这些 u043f u043e u043b u0438 u0430的新组合物,包括用于保护r u0430 u0441 u0442 u0435 u043d u0438 u0439的药物,化妆品,减肥食品或药物 u043c u0438 u043d u043e u043a u0438 u0441 u043b u043e u0442 u0430 u0445。本发明的目的是提供一种新的聚合物材料,该材料可用作矢量图形编辑器的起始产品。并且满足所有要求: u0431 u0438 u043e u0441 u043e u0432 u043c u0435 u0441 u0442 u0438 u043c u043e u0441 u0442 u0438, u0431 u0438 u043e u0434 u0435 u0433 u0440 u0430 u0434 u0438 u04 40 u0443 u0435 u043c u043e u0441 u0442 u0438,能够在体内轻松地缔合或溶解大量活性成分并在体内早期释放活性成分。本发明实现了这一目标,它涉及一种新的 u043e u043b u0438 u0433 u043b u0443 u0442 u0430 u043c u0430 u0442 u0430 u043c u0438,已修改 u043a u0430 u0442 u0438 u043e u043e u043d u043d u044b u043c组,如果可以是 u0434 u0435 u043f u0440 u043e u0442 u043e u043d u043d u0438 u0440 u043e u0432 u0430 u043d u044b是pK,等于或大于7,并且 u0433 u0438 u0434 u0440 u043e u0444 u043e u0431 u043d u044b u043c u0438包含8至30个碳原子的基团,例如 u043f u043e u043b u0438 u0433 u043b u043b u0443 u0442 u0430 u043c u0430 u0442 u044b,已修改的 u043a u0430 u0442 u0438 u043e u043d u043d u044b u043c u0438组,简单而经济高效的向量图形编辑器粒子已启动,并且这些粒子能够形成稳定的水溶液 u043a u043e u043b u043b u043e u0438 u0434 u 043d u044b u0435悬浮液。此类改性的 u043f u043e u043b u0438 u0433 u043b u0443 u0442 u0430 u043c u0430 u0442 u044b具有比其他类似聚合物低粘性的优点与松鼠(例如,胰岛素)的同时保存能力和 u0441 u0441 u043e u0446 u0438 u0438 u0440 u043e u0432 u0430 u0442 u044c其中一些 u0440 u0430 u0441 u0442 u0432 u043e u0440 u0438 u043c u044b在酸性pH值的水中并在生理pH值下不溶(7.4),因此应在注射后就地沉积在皮肤中。

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