Synthesis and Biological Activities of 1,2,4-Triazine Derivatives

摘要

To sdudy the synthesis and biological activities of 1,2,4-triazine derivatives, a series of 1,2,4-triazines were prepared from the reaction of 3-mercapto-5-hydroxyl-6-methyl-1,2,4-triazine with alkyl halide. The structures of prepared compounds were confirmed by IR, ~1H-NMR and elemental analysis. Biological activities showed the compounds had anti-inflammatory activities.