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The Stem Cells meet the Physics Big Machines

机译:干细胞符合物理大机器

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摘要

Stem cell based regenerative therapies involve the administration of selected stem cell populations with the purpose of repairing and regenerating damaged or diseased tissue. Currently available methods of monitoring transplanted cells are quite limited because they have to offer non-destructive strategies capable to identify the location, magnitude, and duration of cellular survival and their fate both at early and late stages. The recent development of imaging techniques offers great potential to address these critical issues by non-invasively tracking the fate of the transplanted cells. This article offers a focused presentation of some examples of the use of imaging techniques connected to the nanotechnological world in research areas related to stem cells. In particular, investigations concerning stem cell treatment of Duchenne muscular dystrophy, Infarcted Heart and bone tissue engineering in animal models are discussed.
机译:干细胞的再生疗法涉及施用所选择的干细胞群,目的是修复和再生受损或患病组织。目前可用的监测移植细胞的方法非常有限,因为他们必须提供能够在早期和晚期阶段识别细胞生存的位置,幅度和持续时间的非破坏性策略。最近的成像技术的发展提供了通过非侵入性传输细胞的命运来解决这些关键问题的巨大潜力。本文提供了一些专注于使用与干细胞相关的研究领域连接到纳米技术世界的成像技术的一些例子。特别地,讨论了动物模型中鼻塞肌营养不良,梗死心脏和骨组织工程的干细胞治疗的研究。

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