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Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H_(22) Cells in Mice

机译:茶多糖和多酚在小鼠肝癌H_(22)细胞生长抑制中的作用比较

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The effects of tea polysaccharides (TPS) and polyphenols (TPP) on the growth inhibition of hepatoma H_(22) cells in mice including the roles of them in immune stimulation were investigated. The results showed that TPS and TPP both significantly inhibited the growth of H_(22) transplantable tumor in mice without statistical difference, both remarkably decreased the spleen index and increased the thymus index compared with that of model group (p<0.05). In addition, TPS and TPP significantly improved the splenocyte proliferation induced by ConA or LPS, and notably enhanced the macrophage phagocytosis towards neutral red. The comparison showed the effect of TPS on immune stimulation was superior to that of TPP to some extent.
机译:研究了茶多糖(TPS)和多酚(TPP)对小鼠中肝癌H_(22)细胞的生长抑制的影响,包括在免疫刺激中的作用。结果表明,TPS和TPP两者都显着抑制了小鼠中的H_(22)移植肿瘤的生长而不统计差异,与模型组相比,脾脏指数显着降低并增加了胸腺指数(P <0.05)。此外,TPS和TPP显着改善了CONA或LPS诱导的脾细胞增殖,并且显着提高了巨噬细胞吞噬作用朝向中性红色。比较表明,TP对免疫刺激的影响优于TPP在一定程度上。

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