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REMOTE MULTISENSING OF BIOLOGICAL SYSTEMS

机译:远程多用户的生物系统

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摘要

The promise and potential of biotechnology rests, ultimately, on our understanding of biological processes at a molecular level. Such understanding allows manipulation and modulation of complex biochemical, metabolic and genetic processes in microorganisms, plants, animals and humans. The vast beneficial potential in manipulating biological processes and systems derives from the diversity of biological organisms and their inherent versatility and adaptability, as reflected in their validation of Darwinian paradigms concerning evolution and natural selection. Within living systems, the obviously chaotic nature of diversity based biological environments is transformed into complex and intricate physiological structures and biochemical pathways based on spatial and temporal organization of an organism's biochemical components. Utilizing structures and pathways, the myriad possible chemical consequences inherent in a collection of molecules in living systems reduces to organized metabolic processes. This ordered biochemical architecture in living systems is based almost entirely on molecular recognition and biospecificity. It is, therefore, through intervention of selective effectors, inhibitors, substrates, hormones and other pairs of transmitter and receptor molecules that living organisms maintain control over the course of chemical change within their systems. Examples of such control range from control of gene expression to self/non self discrimination via the immune system. Biotechnology, in essence, attempts to exploit the known factors affecting the flow of chemical information in biological systems for human use.
机译:生物技术的承诺和潜力最终依赖于我们对分子水平的生物过程的理解。这种理解允许在微生物,植物,动物和人体中操纵和调节复杂的生物化学,代谢和遗传过程。操纵生物过程和系统的巨大有益潜力来自生物生物的多样性及其固有的多功能性和适应性,反映在他们对进化和自然选择的达尔文范式的验证中。在生活系统中,基于生物化组分的空间和时间组织的复杂和复杂的生理结构和生物化学途径的显而易见的基于生理结构和生化途径的明显混乱。利用结构和途径,活性系统中分子集合中固有的无数可能的化学后果减少到有组织的代谢过程。这种有序的生物化学建筑在生活系统中几乎完全基于分子识别和生物创性。因此,通过选择性效应,抑制剂,底物,激素和其他对发射器和受体分子的干预是,生物体维持在其系统内的化学变化过程中的控制。这种控制范围的实例范围从基因表达到通过免疫系统的自主鉴别的控制。实质上,生物技术试图利用影响人类使用生物系统中化学信息流动的已知因素。

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