ANTI-INFLAMMATORY EFFECT OF POLYSACCHARIDES FROM CYNANCHUM WILFORDII OH DEXTRAN SODIUM SULFATE-INDUCED ACUTE COLITIS IN MICE AND LPS-INDUCED MACROPHAGES

摘要

In recent years, polysaccharides of plant origin have been proven as important bioactive components[1]. We recently reported on the immune-enhancing effects of a high-molecular-weight polysaccharide fraction of Cynanchum wilfordii (HMFO) in macrophages and immunosuppressed mice[2]. Cynanchum wilfordii Hemsley is arguably the most-well known species in Asia and it has been reported to alleviate rheumatoid arthritis, vascular diseases and ischemia-related diseases [3,4].