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CHARACTERIZATION OF A NOVEL EXOPOLYSACCHARIDE PRODUCED BY BIFIDOBACTERIA BREVE JCM7017

机译:Bifidobacteria Brive JCM7017产生的新型外糖的表征

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摘要

Bifidobacterium is an important bacterial genus and in the first few months of life it constitutes an significant component of the microbiota of the gastrointestinal tract of healthy humans. There has been much recent interest in specific strains of bifidobacteria as their presence in the gut microbiota has been linked to a range of health benefits and a number of strains are considered as probiotic organisms. In order to exert a probiotioc effect bacteria need to be able to colonise a host. Comparative genomic studies have suggested that the synthesis of exopolysaccharides (EPS) is one strategy adopted by bacteria to enhance their ability to colonise hosts. A number of different Bifidobacteria breve strains have been found in human milk, in the adult gut and in the human vagina. At the same time genomic studies have identified that B breve strains have the capacity to synthesis EPS but todate the structures of these polysaccharides are not known.
机译:双歧杆菌是一种重要的细菌属,并且在生命的前几个月内,它构成了健康人类胃肠道微生物群的重要组成部分。最近近来的双歧杆菌菌株的兴趣是因为它们在肠道微生物群中的存在与一系列健康益处相关,并且许多菌株被认为是益生菌生物。为了发挥益菌效应,细菌需要能够殖民宿主。比较基因组研究表明,潜水糖(EPS)的合成是细菌采用的一种策略,以增强其殖民宿主的能力。在人乳中发现了许多不同的双歧杆菌菌株,在成人肠道和人类阴道中发现。同时,基因组研究已鉴定出B Breve菌株具有合成EPS的能力,而是待染色这些多糖的结构是不知道的。

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