Moraxella catarrhalis is a Gram-negative pathogen that, along with Streptococcus pneumoniae and nontypeable Haemophilus influenzae, is responsible for 15-25% of cases of otitis media (middle ear infection) in children. There is a high incidence of otitis media cases in infants in developed countries with at least 80% contracting the disease before the age of 3 years. M. catarrhalis also contributes to a range of respiratory tract infections in adults and exacerbates serious conditions such as chronic obstructive pulmonary disease (COPD), a leading cause of mortality in the US. Currently, there are no licensed nontypeable M. catarrhalis vaccines available for prevention of otitis media.
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机译：Moraxella catarrhalis是一种革兰氏阴性病原体，与肺炎链球菌和无卵泡血液贫血血流感，负责儿童中耳炎（中耳感染）的15-25％。发达国家中婴儿的中耳炎患者发病率高，至少80％的疾病在3年前收缩。 M. Catarrhalis还有助于成人的一系列呼吸道感染，加剧了慢性阻塞性肺病（COPD）的严重病症，是美国死亡率的主要原因。目前，没有可用于预防中耳炎的许可的无卵型M. catarrhalis疫苗。
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