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Quantification of a Model Protein Lysozyme and MUC5AC-13 Peptide in Serum Matrix Using LC-QTOF

机译:使用LC-QTOF在血清基质中的模型蛋白溶菌酶和MUC5AC-13肽的定量

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1. Q-TOF has been proven to be a great platform for both qualitative and quantitative analysis of large molecules. 2. For peptide MUC5AC-13, three orders of magnitude linear dynamic range were achieved from 0.02 - 10mg/mL in MS scan, targeted MS/MS and auto MS/MS mode. 3. For protein lysozyme, two orders of magnitude linear dynamic range were achieved from 0.01 - 1mg/mL in MS scan mode. Acknowledgements: Richard Edom, Wenying Jian, Naidong Weng from J&J-PRD for the samples.
机译:1. Q-TOF已被证明是对大分子的定性和定量分析的一个很好的平台。 2.对于肽MUC5AC-13,在MS扫描,靶向MS / MS和自动MS / MS模式下,从0.02-10mg / ml实现三个幅度线性动态范围。 3.对于蛋白质溶菌酶,在MS扫描模式下,从0.01-1mg / ml实现了两个幅度线性动态范围。致谢:Richard Edom,Wengy Jian,Naidong Weng从J&J-PRD进行样品。

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