QUANTITATIVE ANALYSIS OF EMPAGLIFLOZIN IN HUMAN PLASMA BY AUTOMATED 96-WELL SOLID PHASE SUPPORTED LIQUID EXTRACTION AND LC/MS/MS

机译：通过自动化96孔固相管液萃取和LC / MS / MS的液相血浆中Empagliflozin的定量分析

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A simple and sensitive automated 96-well SLE LC/MS/MS assay has been developed and validated for the quantitation of empagliflozin in human plasma. The assay was shown to be accurate, precise, specific, and reliable. The validated LC/MS/MS assay has been used in clincical pharmacokinetic studies and incurred sample re-analysis (ISR) has been carried out and the acceptance criteria have been met.

机译：已经开发了一种简单敏感的自动化96孔SLE LC / MS / MS / MS测定并验证了人体血浆中Empagliflozin的定量。该测定显示为准确，精确，具体和可靠。经过验证的LC / MS / MS测定已用于平面图的药代动力学研究，并进行了样品重新分析（ISR），并满足了验收标准。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2012年||共1页
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Yan Mao; Bailuo Ren; Lois Rowland; Jeffrey X. Duggan;
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中图分类 TB994.5-53;
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QUANTITATIVE ANALYSIS OF EMPAGLIFLOZIN IN HUMAN PLASMA BY AUTOMATED 96-WELL SOLID PHASE SUPPORTED LIQUID EXTRACTION AND LC/MS/MS

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