Speeding up the Dry Blood Spot, Plasma, Urine and Saliva analysis with a new sampling technology using a one step extractions combined with LDTD-MS/MS analysis

摘要

Sample cleanup tip applied to DBS gives comparable results with classic method. Preparation time is reduced to less than a minute for 96 sample using conventional robotic station. Total Workflow is reduced to LDTD-MS/MS analysis time witch is 9 seconds/sample (extraction and analysis combined). Cleaning tip technique work for different matrices and compounds. Low sample volume required: 1 to 3 (mu)l.