In-situ Tissue Tryptic Digestion to Facilitate Peptide Analysis using MALDI-MS Techniques to Investigate Protein Induction in Tumour Vascular Targeted Strategies

摘要

Haemoglobin, implying haemorrhage, can be seen in the tumour models as treatment time with CA-4P increases. MS/MS investigations to identify unknown peaks (Fig 3). Further immunohistochemical investigations to validate peptide identities observable in MS spectra and images generated by MALDI-MSI.