NOVEL BIOMARKER DISCOVERY IN EXTRACELLULAR VESICLES FROM PLASMA FOR COLORECTAL CANCER

机译：来自血浆细胞外囊中的新型生物标志物发现结直肠癌

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Targeted proteomics using SRM has been proved to be highly sensitive and quantitatively accurate. However, it is expensive and time-consuming to perform large-scale SRM analysis. We introduce a systematic and scalable SRM workflow for discovery and validation of novel biomarkers in plasma extracellular vesicles (EVs) targeting more than 400 proteins effectively.

机译：使用SRM的靶向蛋白质组学被证明是高度敏感和定量准确的。然而，执行大规模的SRM分析昂贵且耗时。我们介绍了一种系统和可扩展的SRM工作流程，用于发现和验证血浆细胞外囊泡（EVS）中的新型生物标志物，有效地靶向400多种蛋白质。

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《International Mass Spectrometry Conference》|2018年|p1-627|共2页
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Keiko Kasahara; Ryohei Narumi; Yoshihiro Shimizu; Keiko Masuda; Satoshi Nagayama; Takeshi Tomonaga; Yoshiharu Sakai; Jun Adachi;
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中图分类分析化学;
关键词
extracellular vesicles; plasma; biomarker; colorectal cancer;

机译：细胞外囊;血浆;生物标志物;结直肠癌;

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专利

1. Analytical Pipeline for Discovery and Verification of Glycoproteins from Plasma-Derived Extracellular Vesicles as Breast Cancer Biomarkers [J] . I-Hsuan Chen, Hillary Andaluz Aguilar, J. Sebastian Paez Paez, Analytical chemistry . 2018,第10期

机译：从血浆衍生细胞外囊泡的糖蛋白发现和验证作为乳腺癌生物标志物的分析管道
2. Urinary extracellular vesicle biomarkers in urological cancers: From discovery towards clinical implementation [J] . Dhondt Bert, Van Deun Jan, Vermaerke Silke, The international journal of biochemistry and cell biology . 2018,第期

机译：泌尿外细胞外囊泡生物标志物在泌尿外科癌症：从发现到临床实施
3. The role of extracellular vesicles as biomarkers in colorectal cancer [J] . Lucchetti D., Litta F., Ratto C., Techniques in coloproctology . 2018,第12期

机译：细胞外囊泡作为结直肠癌中的生物标志物的作用
4. NOVEL BIOMARKER DISCOVERY IN EXTRACELLULAR VESICLES FROM PLASMA FOR COLORECTAL CANCER [C] . Keiko Kasahara, Ryohei Narumi, Yoshihiro Shimizu, International Mass Spectrometry Conference . 2018

机译：来自血浆细胞外囊中的新型生物标志物发现结直肠癌
5. Molecular Profiling Plasma Extracellular Vesicles from Breast Cancer Patients [D] . Zhong, Zhenyu. 2018

机译：来自乳腺癌患者的分子分析血浆细胞外囊
6. Profiling Extracellular Long RNA Transcriptome in Human Plasma and Extracellular Vesicles for Biomarker Discovery [O] . Rodosthenis S. Rodosthenous, Elizabeth Hutchins, Rebecca Reiman, 2020

机译：在人血浆和细胞外囊泡中分析细胞外长RNA转录组以寻找生物标志物
7. Profiling Extracellular Long RNA Transcriptome in Human Plasma and Extracellular Vesicles for Biomarker Discovery [O] . Rodosthenis S. Rodosthenous, Elizabeth Hutchins, Rebecca Reiman, 2020

机译：用于人血浆和细胞外囊泡的分析细胞外长RNA转录组，用于生物标志物发现

NOVEL BIOMARKER DISCOVERY IN EXTRACELLULAR VESICLES FROM PLASMA FOR COLORECTAL CANCER

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