Parallel Reaction Monitoring Mass Spectrometry for Histone H3 Modification Analysis of Differentiating MEL Cells

机译：不同反应监测质谱法，用于区分Mel细胞的组蛋白H3修饰分析

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Quantitative high resolution analysis of H3 histones and their PTMs. WCX-HILIC separated histone peptides based on acetylation and methylation status. Extensive sequence coverage, hundreds of variants identified using ETD. More acetylations and more methylations in HDAC-treated samples (embryonic Hb). Accurate count of total number of modifications on entire N-terminus. Developed bioinformatics pipeline for analysis.

机译：H3组蛋白及其PTM的定量高分辨率分析。基于乙酰化和甲基化状态，WCX-HILIC分离的组蛋白肽。广泛的序列覆盖，使用ETD确定了数百种变体。在HDAC处理的样品（胚胎HB）中更多的乙酰化和更多的甲基化。准确计数整个N-Terminus的整个修改总数。开发的生物信息学管道进行分析。

著录项

来源
《ASMS Conference on Mass Spectrometry and Allied Topics》|2016年|1CD|共1页
会议地点
作者
Michael J Sweredoski; Annie Moradian; Matthias Raedle; Sonja Hess;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB994.5-53;
关键词

相似文献

外文文献
中文文献
专利

1. Mass spectrometry analysis of the variants of histone H3 and H4 of soybean and their post-translational modifications [J] . Tao Wu, Tiezheng Yuan, Sau-Na Tsai, BMC Plant Biology . 2009,第1期

机译：大豆组蛋白H3和H4变体及其翻译后修饰的质谱分析
2. Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications [J] . Johnson L, Mollah S, Garcia BA, Nucleic Acids Research . 2004,第22期

机译：拟南芥组蛋白H3的质谱分析揭示了翻译后修饰的不同组合
3. Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications [J] . Benjamin A. Garcia, Donald F. Hunt, Jeffrey Shabanowitz, Nucleic acids research . 2004,第22期

机译：拟南芥组蛋白H3的质谱分析揭示了翻译后修饰的不同组合
4. Parallel Reaction Monitoring Mass Spectrometry for Histone H3 Modification Analysis of Differentiating MEL Cells [C] . Michael J Sweredoski, Annie Moradian, Matthias Raedle, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：不同反应监测质谱法，用于区分Mel细胞的组蛋白H3修饰分析
5. Quantitative mass spectrometry: Proteomic analysis of differentiation of MEL cells treated with hexamethylene bisacetamide and 7-[N-(3-aminopropyl)amino] heptan-2-one. [D] . Hawke, David H. 2004

机译：定量质谱：用六亚甲基双乙酰胺和7- [N-（3-氨基丙基）氨基]庚烷-2-酮处理的MEL细胞分化的蛋白质组学分析。
6. Mass spectrometry analysis of the variants of histone H3 and H4 of soybean and their post-translational modifications [O] . Tao Wu, Tiezheng Yuan, Sau-Na Tsai, 2009

机译：大豆组蛋白H3和H4变体及其翻译后修饰的质谱分析
7. Analysis of Histones in Xenopus laevis: II. MASS SPECTROMETRY REVEALS AN INDEX OF CELL TYPE-SPECIFIC MODIFICATIONS ON H3 AND H4* [O] . Nicklay, Joshua J., Shechter, David, Chitta, Raghu K., 2008

机译：非洲爪蟾的组蛋白分析：II。质谱揭示了H3和H3细胞特定类型修饰的指数 H4 *

Parallel Reaction Monitoring Mass Spectrometry for Histone H3 Modification Analysis of Differentiating MEL Cells

摘要

著录项

相似文献

相关主题

期刊订阅